* Nordic example shown, package may vary by country and region
Fasten the plunger rod into the rubber stopper of the syringe by turning the plugger rod clockwise until it stops.
Remove the blue cap of the powder vial
Penetrate the stopper of the powder vial with the Mini-Spike transfer device
Remove the cap from the syringe and keep it for later use
Hold the syringe upright and carefully press the plunger rod upward to remove air
Connect the syringe to the Mini-Spike transfer device
Inject about 10 ml of the solvent into the powder vial
The vial should be about ¾ full
Without withdrawing the Mini-Spike from the vial, hold the powder vial and the syringe in a firm grip
Shake gently to ensure complete dissolution
Withdraw all of the dissolved solution from the powder vial into the syringe
Disconnect the empty vial and Mini-Spike transfer device from the syringe
Plug the syringe with the syringe cap
Gently mix the contents of the syringe
Hexvix is now reconstituted and ready for use
The appearance of the reconstituted solution is clear to slightly opalescent, and colorless to pale yellow
Ensure that the bladder is completely empty prior to Hexvix instillation
Patients should be catheterised
Connect the syringe containing Hexvix to the catheter using Luer-Lock
Gently instill 50ml of Hexvix into the bladder
Hexvix® reconstitution – additional notes11
